Low Dose Naltrexone (LDN) Update

Eleven days after starting LDN I can report a subtle deepening of sleep which occurred immediately, and now I  am getting up only once in the middle of the night to pee. Also, strangely, the first effect I noticed was that my facial skin seemed softer. I can only imagine that some kind of low-level inflammation was causing roughness of my skin.

I noticed that one night when I forgot to take my dose before going to sleep, and woke up and took it around three or four in the morning, I had a crummy day the next day. As I understand it, the dose should be taken before bed or before a normal bedtime whether you go to sleep or not. There is evidently a window of time from between 2 and 3 AM when the LDN works to reset the body's opiate receptors. I guess I missed it that night, because the next day I was out of sorts and uncomfortable.

The next night I took it around midnight or 12:30 and it seemed okay the next day.

I will keep you posted going forward!